How to Use DMSO for Weight Loss: Is it Really Effective or Just Hype?

How To Use DMSO for Weight Loss

In my exploration of health benefits and weight loss strategies, I’ve encountered DMSO (dimethyl sulfoxide), a FDA-approved drug known for its pain-relieving properties. Often found in online medical shops, DMSO, primarily used as a prescription medication, has been touted by some as a helpful addition to the weight loss journey.

However, the scientific proofs of DMSO directly contributing to weight loss are not as concrete as one might hope. Its effectiveness lies more in the realm of reducing muscle soreness and joint pain, particularly in conditions like arthritis. Its role as a natural anti-inflammatory treatment is where DMSO truly shines. This can indirectly support weight loss efforts by enabling more comfortable and thus more consistent exercise routines. But expecting DMSO to directly influence weight loss might lead to disappointment. For a more detailed insight, a blog post or dedicated literature on the topic can be enlightening. As with any health supplement or drug, it’s crucial to learn about it thoroughly and consult healthcare professionals before use.

The Ultimate Guide to Using DMSO Safely: Tips and Tricks

When incorporating DMSO into your routine, particularly for weight loss, which notably lacks FDA approval, it’s crucial to apply it correctly to clean, dry skin. Avoid areas that are broken, irritated, or inflamed to minimize adverse effects. While applying, wear gloves to prevent irritation to your hands. Always follow the instructions provided by the healthcare professional or the manufacturer to avoid dangerous outcomes from improperly using the product. Additionally, be cautious about exposing the treated area to extreme heat or cold.

Be aware that DMSO has a distinctive odor which some individuals may find unpleasant; use it in a well-ventilated area to mask the smell. It’s especially important for those who are pregnant, breastfeeding, or have medical conditions like liver or kidney disease, to avoid using DMSO, as it can be harmful. If you notice signs like redness or itching, stop using the product immediately and contact a healthcare provider. Despite its potential benefits, DMSO should always be used under supervision and with informed guidance.

2 Best Ways To Use DMSO For Weight Loss

Understanding DMSO: A Versatile Compound

DMSO (Dimethyl sulfoxide), an odorless, colorless, non-toxic organic solvent, has gained popularity in various fields including scientific, medical, and industrial research. Originally a byproduct in the wood industry, specifically in the processing of paper, DMSO has become a topic of interest in many articles related to weight loss. Its ability to penetrate cell membranes effectively makes it a unique compound in medical applications.

DMSO’s Role in Weight Management

In recent years, DMSO has garnered attention for its potential as an aid in weight loss. Studies have suggested that DMSO might help break down fat cells, reduce inflammation, and improve insulin sensitivity, all of which could potentially lead to weight loss. This potential has made DMSO a curious and good topic for those searching for useful and innovative weight loss methods.

Utilizing DMSO as a Topical Agent

One of the best ways to use DMSO for weight loss is topically. Due to its anti-inflammatory and analgesic properties, applying DMSO directly to the skin can provide pain relief and reduce swelling. This can be particularly beneficial for individuals engaging in physical activities as part of their weight loss regimen.

The Liquid with Powerful Properties

As a liquid with powerful properties, DMSO serves as more than just a pain reliever; it’s a multifaceted compound that could aid in health and weight management. However, it’s important to acknowledge the health risks associated with improper use.

Steps to Safe Usage

The key to effectively using DMSO for weight loss lies in understanding the correct steps for its safe usage. Whether you’re using it to enhance your workout recovery or as part of a targeted treatment plan, being informed about the right way to apply and handle DMSO is crucial.


Choosing the Right Concentration of DMSO

When using DMSO as a liquid for weight loss, selecting the appropriate concentration is key. DMSO is available in various concentrations, typically from 70% to 99%. The higher the concentration, the stronger the effects. Your choice should align with the intended use and personal preference.

Preparing the Area for Application

Ensure the fat area where DMSO will be applied topically is clean and dry. This preparation is crucial for proper absorption. The effectiveness of DMSO significantly depends on the preparation of the skin.

Diluting DMSO for Safe Use

If using a high concentration of DMSO, it may be necessary to dilute it with a neutral substance such as distilled water, as per the manufacturer’s instructions. Proper dilution is essential for safe application.

Applying DMSO Correctly

Apply DMSO using a dropper, dispensing a small amount and rubbing it gently into the skin as needed. Ensure the area is properly covered for the DMSO to work effectively.

Allowing DMSO to Absorb

Let the DMSO absorb into the skin for 15-20 minutes before covering with clothing or bandages. This time is crucial for the DMSO to be fully absorbed.

Post-Application Care

After application, wash your hands thoroughly to avoid accidental ingestion or contact with sensitive areas such as the eyes and mouth. This step prevents potential side effects.

Consulting a Healthcare Professional

Always consult a healthcare professional before using DMSO, as it lacks FDA approval for this use. Improper use can cause serious health risks, including skin irritation, respiratory issues, and liver damage.


DMSO Cream: An Effective Topical Medication

DMSO cream, a form of dimethyl sulfoxide, is a topical medication known for relieving pain and reducing inflammation. As part of a weight loss strategy, it’s important to follow a strict guideline for safe and effective use.

Preparing for Application

Before applying the cream, always wash your hands thoroughly with soap and water. This step is crucial to avoid transferring bacteria or dirt to the fat area where the cream will be applied.

Cleaning the Affected Area

Ensure the affected area is clean. Wash it with soap and water and pat it dry with a clean towel. This preparation is key for the DMSO cream to work effectively.

Applying the Cream

Apply a small amount of the DMSO cream and rub it into the skin until it’s fully absorbed. Correct application ensures that the active ingredients are utilized effectively.

Repeat Applications for Best Results

For optimal results, repeat the application twice daily, or as recommended by a healthcare professional. Be mindful of the dosage and frequency to avoid overuse.

Storing DMSO Cream

Store the cream properly in a cool, dry place, away from direct sunlight and heat. Ensure it’s out of reach of children and pets to prevent accidental misuse.

Seeking Guidance From Healthcare Professionals

It’s vital to consult healthcare professionals for guidance, especially since DMSO cream can be a prescription medication. Improper use may cause skin irritation, allergic reactions, or other side effects. If adverse reactions occur, stop using the product and contact your provider immediately.

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What Are The Benefits And Risks Of Using Dmso For Weight Loss?

DMSO has been studied for its potential health benefits, particularly in reducing inflammation and pain. This aspect makes it an intriguing option for those looking to support their weight loss efforts. The reduction of inflammation can be particularly beneficial in easing discomfort associated with exercise, thereby potentially aiding in more consistent physical activity, a key component of any weight loss regimen.

However, the use of DMSO for weight loss does not come without its challenges. It can pose serious health risks, including skin irritation, respiratory issues, and even liver damage if not used correctly. These risks highlight the importance of approaching DMSO with caution and under the guidance of a healthcare professional, especially considering its primary application is not for weight loss.

Some Of The Potential Benefits Of DMSO Include:

DMSO is renowned for its effectiveness in reducing inflammation and pain, making it a valuable treatment option for various conditions. It has shown promising results in managing conditions like arthritis and fibromyalgia, where inflammation and pain are significant challenges. This aspect of DMSO might indirectly support weight loss efforts by alleviating discomfort, thereby enabling more consistent and effective exercise routines.

Another notable benefit of DMSO is its role in improving circulation by dilating blood vessels. This property can be a significant benefit for individuals suffering from conditions like Raynaud’s disease or peripheral artery disease. Improved circulation not only enhances overall health but can also aid in the recovery process post-exercise, which is crucial for those on a weight loss journey.

Furthermore, DMSO is known for promoting healing and helping to reduce scarring in wounds and burns. This healing aspect may not directly contribute to weight loss but is an added advantage for overall skin health and recovery, which can be important for those engaging in regular physical activity as part of their weight loss plan.

What Are the Risks of Using DMSO?

When considering the use of DMSO for weight loss, it’s essential to be aware of the frequent side effects and potential risks. As someone who has navigated the complexities of using various supplements, I’ve learned that understanding these risks is crucial for making informed decisions.

DMSO, a solvent used in the market, is known for being absorbed through the skin. Its application can lead to skin irritation, a strong odor resembling garlic, and in some cases, stomach upset. These side effects are relatively common and should be considered before starting a DMSO regimen. From my personal experience, the discomfort from these side effects can be quite significant, especially when DMSO is used without proper guidance.

Moreover, there are serious health effects associated with the use of industrial-grade DMSO, which may contain impurities. The use of non-medical grade DMSO can lead to serious allergic reactions, including headaches, itching, burning when applied, and even deadly reactions at high concentrations. When it is taken by mouth, it can cause dizziness, drowsiness, nausea, vomiting, diarrhea, constipation, and a decreased appetite.

Another critical aspect to consider is the interaction of DMSO with other medications. DMSO can increase the effect of certain medicines, particularly blood thinners, steroids, and sedatives. This is a significant concern because it can lead to unexpected complications. From my perspective, this interaction is often overlooked but is among the biggest concerns. It’s also crucial to wash your hands after applying DMSO, as it’s a solvent that can cause anything absorbed through the skin to enter the bloodstream.

For pregnant or breastfeeding individuals, DMSO is not recommended. There is little known about its effects on the fetus or infant. Additionally, individuals should not use DMSO without talking to a doctor, especially if they have diabetes, asthma, liver, or kidney conditions.

It’s important to keep in mind that supplements, unlike drugs, are not regulated by the FDA. This means that the manufacturer does not have to prove that their product is safe or effective before selling it. This lack of regulation can lead to variability in product quality and potential risks.

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What Are The Recommended Doses Of Dmso For Weight Loss?

For those thinking of using DMSO for weight loss, it’s important to know exactly how much to use. As someone who has explored various weight loss methods, I understand the importance of getting the dosage right. Medical professionals recognize DMSO as a potent chemical that has been used for a considerable period of time in different forms like creams, gels, and liquids, depending on one’s own needs to lose weight.

To reduce wrinkles or freeze tissues, a cream with 1-2% DMSO can work well. If you are trying to achieve more targeted weight loss, you might need higher concentrations. However, for body goals, it’s recommended to use levels no higher than 15% to lower the risk of side effects. Be careful not to apply too much, as excessive amounts can cause skin irritation. Always start with a small dose and observe how your body reacts.

The strength and complexity of DMSO make it a challenging compound to use correctly. Fortunately, there are numerous online sources, like blogs, forums, and medical websites, offering valuable insights on how to safely use DMSO for various purposes, including boosting collagen. These platforms allow individuals to share their experiences and advice, helping other users to achieve effective results while ensuring safety.

How To Properly Store DMSO: Tips and Tricks

In the journey of using DMSO for weight loss, knowing how to store it correctly is as crucial as understanding its application. DMSO should be kept in a cool, dry place, away from sunlight and heat sources. I’ve learned that proper storage significantly affects the efficacy and safety of this compound. Ensure it’s stored in a tightly closed container to prevent contamination and evaporation. The ideal room temperature for storing DMSO is between 20-25°C (68-77°F).

It’s vital to note that DMSO poses a high flammability risk. This chemical absorbs into various materials like plastic and rubber, so containers made of stainless steel or glass are recommended. Also, keep it away from any open flames. From my experience, understanding and respecting the chemical properties of DMSO is essential for safe handling.

One crucial aspect to remember is do not freeze DMSO. Freezing may cause the formation of crystals, which can compromise its effectiveness. If you notice crystals, warm the container slightly and swirl gently to re-dissolve them. This is a simple but essential step in maintaining the integrity of the product.

Lastly, it’s important to regularly check the expiration date of your DMSO. Discard any expired product, as it can become dangerous and ineffective over time. In my personal experience, keeping a vigilant eye on these details ensures that the product you are using is both safe and effective for your weight loss journey.

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Why Do People Use DMSO?

DMSO is a compound that has garnered attention for its potential to relieve pain in conditions like osteoarthritis. As someone with a keen interest in alternative health solutions, I’ve noted that DMSO is also considered an alternative cancer treatment by some, despite a lack of widespread scientific endorsement. People often turn to DMSO to treat wounds, burns, and various injuries, and it has been explored for conditions like headache, rheumatoid arthritis, eye problems, scars, scleroderma, and scar tissue.

However, it’s crucial to highlight that, despite being available as a prescription medicine in some cases, there is little to no scientific evidence to support claims of its effectiveness for many of these uses. The American Cancer Society points out that there is no evidence that DMSO can effectively treat cancer, warning against serious delays in getting proper, effective treatment.

A recent analysis of studies showed that DMSO can be significantly more effective than a placebo in managing joint pain, which is one reason for its popularity. However, it’s important to note that there are no studies or guidelines for determining the proper dose for different uses. Typically, a gel concentration of 25% is applied three to four times a day for pain relief. DMSO is sold without a prescription in a range from 10% to 90%. The concentration and frequency of application can vary greatly depending on the intended use.

From my personal perspective, it’s important for users to approach DMSO with caution, considering the lack of comprehensive guidelines and potential side effects. The diverse range of concentrations available over the counter underscores the need for careful consideration and, ideally, consultation with a healthcare professional before beginning use, especially for weight loss.

Are There Any Alternatives to Using Dmso for Weight Loss?

While DMSO has been explored for weight loss, it’s important to consider safe and effective alternatives. In my experience, the most evidence-backed and safe methods for weight loss involve a combination of a healthy diet and regular exercise.

A healthy diet, consisting of a balanced variety of nutrient-dense foods, plays a crucial role. This includes fruits, vegetables, whole grains, lean protein sources, and healthy fats. Equally important is reducing intake of processed, high-fat foods, sugary drinks, and snacks. This approach has consistently been effective in my journey and those of many others I’ve guided.

Regular exercise is another important component of weight loss. It is recommended that adults perform either moderate-intensity exercise or vigorous-intensity exercise each week, complemented by strength training exercises on several days. This not only aids in weight loss but also improves overall health and well-being.

In addition to diet and exercise, there are other weight loss strategies worth considering. Working with a healthcare professional or a registered dietitian to develop a personalized weight loss plan can be incredibly beneficial. Joining a support group or program, and incorporating stress-reducing activities into daily routines can also be effective. It’s always advisable to consult with a healthcare professional before starting a new weight loss program to ensure it is safe and appropriate for your individual needs and medical history.


In limited research, DMSO has been explored for weight loss, with some reported success. However, it’s crucial to approach this with caution and always consult a healthcare professional before starting any new weight loss regimen. While there are recommendations to use DMSO topically for weight loss, using it orally should be avoided to prevent potential harmful side effects. When applying it to the skin, mixing it with a carrier oil such as coconut oil or olive oil can reduce risks. It’s also important to follow proper safety protocols when using DMSO, like wearing gloves, avoiding contact with eyes, mucous membranes, and open wounds, and performing a patch test before applying it to a larger area of skin to prevent skin irritation. In addition to DMSO, maintaining a healthy diet and exercising regularly are key to achieving safe and sustainable weight loss.


1. What Are The Side Effects Of Dimethyl Sulfoxide?

When using DMSO (dimethyl sulfoxide) for weight loss, it’s important to be aware that it can induce histamine release, which is a reason for several adverse reactions. These reactions include flushing, dyspnoea (difficulty in breathing), abdominal cramps, and various cardiovascular reactions. Being informed about these potential side effects is crucial for anyone considering the use of DMSO in their weight loss journey.

2. When Should You Not Use Dmso?

You should not use DMSO for weight loss without talking to a doctor, especially if you have conditions like Diabetes, Asthma, or any Liver or kidney conditions. These medical issues can complicate the effects of DMSO, making it crucial to get professional medical advice before considering its use.

3. Is It Safe To Drink Dmso?

Industrial grade DMSO is not intended for human use as it may contain contaminants that can cause serious side effects. Therefore, it is critical to understand the FACTS and the BOTTOM LINE about its use as a weight loss aid: for most people, drinking DMSO, especially industrial grade, is unsafe and not recommended.

4. Can You Put DMSO Directly On Your Skin?

DMSO can be applied to the skin and is often used topically. Although it is available as a prescription medicine and sometimes as a dietary supplement, it should be noted that it is not commonly taken by mouth for weight loss. In medical scenarios, DMSO can be injected into veins or used intravenously (by IV), mainly in the management of amyloidosis and its related symptoms. However, when considering its use for weight loss, topical application is the most common method.

5. Does DMSO Affect Your Sleep?

In contrast to other substances, the effects of DMSO on sleep are not widely understood. However, there is some data concerning sleep apnea and sleep efficiency. A measured effect was noted with dronabinol in a solution containing 25% DMSO, where it reduced REM sleep, in line with previous work by Carley et al. using 100% DMSO. This suggests that DMSO could potentially influence sleep patterns, particularly REM sleep, although more research is needed in this area specifically for weight loss contexts.

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